Does the one touch work on the windows when in car?
If not then simple reset of the system will do this, just roll the windows down, up down up by holding the windows switches in place, then it should reset comfort to one touch which inturn also resets for the remote
You can check 46, 42 & 52 for any codes thrown, 42 is drivers door module, 52 is passengers & 46 is conveneince which has all the comfort features in long coding, but these codes dont change by themselves, its most likely a reset needed thats all
Do me a favour, go into 46, then click on coding, then click long coding, make sure the number 4, bit tick boxes are there at bottom, then come out alltogether, then go back in to same place & tell me if the tick boxes have disappeared as might have found a bug today with vcds as mate has same problem, tick boxes disappear on 2nd time of going into long coding weird, but need to confirm its not just us before reporting