There are two small nipples on the master cylinder that quite often don't get bled. If you let too much fluid out of the system or let the reservoir empty air will find it's way to the master cylinder and these may need bleeding.I use a pressure bleeder about 10-15 PSI max and always managed to bleed the system. Too much pressure with a pressure bleeder can cause the fluid reservoir to split but it also stops fluid moving through certain parts of the ABS because of a valve.
This is copied from Elsa Win and is possibly where some people go wrong trying to bleed the brake system.
"When using a brake system filling and bleeding appliance (such as VAS 5234 or V.A.G 1869 A) to replenish the brake fluid, make sure that filling pressure does not exceed 1 bar.
If the filling pressure exceeds 1 bar, a hydraulically controlled change-over valve (which is required for the EDL function) prevents unrestricted flushing of the EDL-related parts of the hydraulic unit. If this is the case, it may not be possible to bleed the system properly.
For this reason the brake fluid pressure must be reduced to 1 bar on the brake filling and bleeding appliance."