I bought a DMR-E50 about two years ago. I'm not sure if that's the same as the one you're considering. I'm guessing the "H" in the title means it's got a hard-drive, which mine hasn't.
When I bought mine, I paid £280, & it was considered the best you could get at that price-point (up to £300). Since then, as is inevitable, lots of newer model have come onto the market, specs & performances have gone up, and prices have gone down.
I bought mine to replace an elderly VCR & a stand-alone budget DVD player. Within that term of reference, it was an excellent choice. However, since then I've got a Sky+ box, so I rarely use the Panasonic for day-to-day watch-and-wipe recording purposes, the exception being where there are three progs I want to see, all on at the same time.
I've also now got a DVD-R drive on my PC, so if I'm making a permanent copy of a DVD, I'll generally do it on the PC, not the Panasonic.
It only really gets used as a DVD player now, and the lack of a component output means I can't use the progressive-scan facility on the TV that I bought six months after I bought the Panasonic. As just a player, it doesn't match the performance of a Toshiba SD350, which you can buy for £79. So, a high-performing best-buy product has become near-redundant in the space of two years, due to no particular fault of its own.
So, what I think I'm trying to say is before you buy, think very carefully not just about whether it meets your current needs, but but whether it will still do everything you might want it do even in as little as a year's time.