8" 45 offset might catch slightly if you lower a lot, depending on the tyre -
this wheel sticks out 17mm more than oem
its difficult to get wheels with such large offsets though - it limits the choice - most replicas are 42 to 45 - the 45 is definitely better.
ive just pickup up some rs6 reps in 46 offset at 8" and am lowered 30mm with 235/40/18 tyres and it doesnt catch at all.
when you lower the car the static camber will get bigger, but there is less camber left in roll, so if your car rolls a lot the camber will not increase enough and you will run out of grip - that usually the front end leading to understeer.
fronts go from about -0.3deg to -1.2 with a drop of 30mm, and the rears ended up to -2, -.8 after some adjustment. the fronts have no adjustment without aftermarket mods but the rears are adjustable. i added adjustable top mounts to give me -1.65 front camber with -30mm drop